Therefore central giant cell granuloma was considered as the differential diagnosis. Central giant cell granuloma of the mandible american. Central giant cell granuloma cgcg is a benign intraosseous lesion of unknown etiology, and occurs in jaws. Central giant cell granuloma cgcg is an uncommon benign intraosseous lesion of the jaw, found predominantly in children and young adults below 30 years of age.
Central giant cell granuloma cgcg is a rare, nonneoplastic, benign lesion that exhibits expansive. An aggressive central giant cell granuloma in a pediatric. A case report elisa fernandezcooke, md a, jaime cruzrojo, md, carmen gallego, mdb, ana isabel romance, mdc, rocio mosquedapena, md, yolanda almaden, mdd, jaime sanchez del pozo, mda abstract tumorinduced osteomalaciarickets is a rare paraneoplastic disorder. The aim was to evaluate the effectiveness of the longterm administration of intranasal calcitonin spray for the treatment of central giant cell granuloma cgcg in a retrospective case study. Multifocal central giant cell granuloma a case report. It is an uncommon tumor in jaws, its etiology and pathogenesis is unknown. Giant cell granulomas in general are mild and rarely present with bony expansion, cortical perforation or.
A central giant cell granuloma in posterior part of. We present the case of a 60yearold woman with preauricular swelling, limitation of joint motion and pain on only the right side. Mar 21, 2012 central giant cell granuloma formerly called as giant cell reparative granuloma is a non neoplastic proliferative lesion of unknown etiology. Central giant cell granuloma, benign jaw tumor, molar, recurrent pericoronitis, multinucleated giant. It occurs most commonly in mandible, but can also occur in maxilla. Central giant cell granuloma cgcg is a benign intraosseous lesion. The article reports the case of central giant cell granuloma, affecting.
Central giant cell granuloma cgcg previously called giant cell reparative granuloma is a nonneoplastic proliferative lesion of unidentified etiology. A case report with diagnostic dilemma garima singh 1, ashish thakur 2, heena sadiq 1, priti gupta 3 1 department of oral and maxillofacial pathology, i. The condition was first identified in 1953 by jaffe, who initially termed this lesion as a central giant cell reparative granuloma, but nowadays the reparative word has been. Radiographic imaging showed radiolucent lesion on right side of lower jaw, well defined, expansile, unilocular. Giant cell granuloma is often confused with giant cell tumour. There are also reports of cgcl with ameloblastoma, and several nonodontogenic fibroosseous lesions 17,18. Tumorinduced rickets in a child with a central giant cell granuloma. Divided into non and aggressive subtypes, the aggressive subtype.
Cgcg treatment and management is challenging for clinicians. After informed consent was obtained, the patient underwent radiotherapy. Peripheral giant cell granuloma is a common benign and reactive gingival epulis in oral cavity. Central giant cell granuloma a case report balaji p, balaji s m. However, a giant cell tumour can be distinguished based on the fact that it occurs commonly between the ages of 25 and 40 years, usually involving the long bones and is more aggressive in nature, with frequent recurrence after curettage. Central giant cell granuloma formerly called as giant cell reparative granuloma is a non neoplastic proliferative lesion of unknown etiology. Cgcg lacks in clinical and radiographical pathognomonic features to distinguish from common lesions occurring in this region. Divided into non and aggressive subtypes, the aggressive subtype is relatively rare and can occasionally progress rapidly, resulting in significant morbidity. This report presents a case of 22 year old female with central giant cell granuloma on right side of mandible.
Case report a twenty two year old female patient reported to department of oral and maxillofacial surgery with chief complaint of painless swelling on right lower side of face since 1 year. We present a child with symptoms of rickets as the first clinical sign of a central giant cell granuloma cgcg with high serum levels of fgf23, a hormone associated with decreased phosphate resorption. The case reported here resembled a wide variety of conditions that led to a misdiagnosis both on clinical and radiographic examinations but was histopathologically diagnosed as cgcg. Extremely aggressive behavior of central giant cell granuloma. This report presents the treatment and management of recurrent, aggressive cgcg after surgical resection. The present report presents a unique case of giant cell lesions of the jaws, wherein a peripheral giant cell granuloma recurred exclusively as a central giant cell lesion in a young patient. However, a giant cell tumour can be distinguished based on the fact that it occurs commonly between the ages of.
Central giant cell granuloma is a benign intraosseous lesion. Central giant cell granuloma of the posterior maxilla. Central giant cell granuloma cgcg of the jaws is a benign, intraosseous, osteolytic lesion of debatable etiology. Case report open access an aggressive central giant cell granuloma in a pediatric patient. Central giant cell granuloma of the mandibular condyle. The low incidence of the lesion in arab countries makes it a rare case report. Central giant cell granulomas are benign tumours of the mandible, presenting in children. Casereport munzenmayer j1, tapia p 2, zeballos j, martinez a 3, compan a4, urra a 5, spencer ml6 summary this case report describes a 19yearold female patient with a central giant cell granuloma in the left mandibular condyle, treated with en bloc resection. Preetha balaji, sm balaji departments of oral and maxillofacial surgery, balaji dental and craniofacial hospital, chennai, tamil nadu, india click. Central giant cell granuloma, benign jaw tumor, molar, recurrent pericoronitis, multinucleated giant cells. The final diagnosis was based on the histopathological report as central giant cell granuloma. A central giant cell granuloma in posterior part of maxillaa. We define a case of central giant cell granuloma ascending from the maxilla to highlight the verdict of this enigmatic lesion.
Central giant cell granuloma of the maxilla bmj case reports. Jul 20, 20 giant cell granuloma is often confused with giant cell tumour. Wed like to understand how you use our websites in order to improve them. Giant cell granuloma gcg is an uncommon, benign, proliferative, intraosseous lesion representing granuloma. S dental college, hospital and research centre, greater noida, india 2 army dental core, central government of india, india 3 department of oral medicine and radiology, i. Tumorinduced rickets in a child with a central giant cell. Central giant cell granuloma cgcg is a relatively uncommon benign bony lesion of a variably aggressive nature, accounting for less than 7% of all benign jaw lesions. This lesion is more common in border of mandible to the upper one third of gaertner. It accounts for almost 7% of all benign lesions of the.
It is twice as common in females and is more likely to occur before age 30. Case report giant cell granuloma of the maxilla usman haider uzbek, iram mushtaq oral and maxillofacial unit, department of dentistry, ayub medical college, abbottabad. It is actually an asymptomatic lesion which becomes evident during routine radiographic examination or as a result of painless but visible expansion of. Central giant cell granuloma is an uncommon benign intraosseus lesion of jaws. Aggressive central giant cell granuloma of the maxilla. The case reported here resembled a wide variety of conditions that led to a misdiagnosis both on clinical and radiographic examinations but was. Peripheral giant cell granuloma or so called giant cell epulis is the most common oral giant cell lesion. Central giant cell granuloma a case report balaji p, balaji. Although central giant cell granulomas cgcgs appear to be benign, their radiographic findings are active. For the previously reported cases in one female and three males, the mean age at presentation was 30 years. Pdf multifocal central giant cell granuloma a case report. Nagargoje department of oral and maxillofacial surgery midsr dental college latur, maharashtra, india corresponding author a b s t r a c t. Central giant cell granulomas are benign tumours of the mandible, presenting in children and young adults.
Surgical treatment and reconstruction for central giant cell granuloma of mandible case report. A recurrent central giant cell granuloma in a young. Pdf central giant cell granuloma of the posterior maxilla. Central giant cell granuloma condyle mandible intraosseous abstract introduction. Radiotherapy for recurrent central giant cell granuloma. Giant cell granuloma gcg is an uncommon, benign, proliferative, intraosseous lesion representing central giant cell granuloma cgcg is a localised benign condition of the jaws. Thought to represent a reparative response to intrabony haemorrhage and inflammation, cgcg was once regarded as a reactive lesion. We herein describe an intriguing case of a 21yearold male patient who was. Central giant cell granuloma cgcg is an uncommon benign bony lesion that occurs in the mandible and maxilla.
Achieving the correct diagnosis is reportedly difficult because cgcgs are very similar to odontogenic jaw tumors. Pdf this article describes a case of central giant cell granuloma in the right posterior region of the mandible in a 10 yearold boy. The case described here involved maxilla which was treated with surgical excision. Central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a nonneoplastic proliferative lesion of an unknown aetiology. It usually presents as a purplishred soft tissue nodule consisting of multinucleated giant. Central giant cell granulomas are more common in the anterior mandible, often crossing the midline and causing painless swellings. An aggressive central giant cell granuloma in a pediatric patient. Central giant cell granulomas of the condyle are rare. Case report a twenty two year old female patient reported to department of oral and. These tumors become severely invasive with the stimulus of surgery, resembling malignant tumors. The true nature of this lesion is controversial and remains unknown. Central giant cell granuloma in a child case report. Central giant cell granuloma cgcg is a relatively uncommon benign bony lesion of a variably aggressive nature. Central giant cell granuloma cgcg is an uncommon, benign, and proliferative lesion of the jaw with an unknown etiology.
Case report open access a peripheral giant cell granuloma. Tumorinduced osteomalaciarickets is a rare paraneoplastic disorder associated with a tumorproducing fibroblast growth factor 23 fgf23. It usually presents as a purplishred soft tissue nodule consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells. Central giant cell granuloma a case report balaji p. Idiopathic bilateral central giant cell granuloma of jaw. Extra oral examination revealed a diffuse swelling on the left side of face causing slight obliteration. Central giant cell granuloma cgcg is a rare, nonneoplastic, benign lesion that exhibits expansive and osteolytic biological behavior. Case report open access radiotherapy for recurrent central giant cell granuloma. Central giant cell granuloma cgcg at operation, intraorally, lesion was defined by who1,4 and described by extended superoinferiorly from the lower 1. Clinically and radiographically difference between. Central giant cell granuloma cgcg is a benign intraosseous lesion that occurs in long bones. It is often difficult to make a clinical diagnosis. Thought to represent a reparative response to intrabony.
We present a case of an aggressive central giant cell granuloma cgcg in a six yearold female. Central giant cell granuloma is a non neoplastic lesion exhibiting a spectrum of clinical behavior. Extra oral examination revealed a diffuse swelling on the left side of face causing slight obliteration of nasio. Surgical treatment and reconstruction for central giant cell. A destructive lesion kaushik sk1, haranal s2, naresh n3.
Recurrent central giant cell granuloma in the mandible. Jul 19, 2019 central giant cell granuloma cgcg is a rare, nonneoplastic, benign lesion that exhibits expansive and osteolytic biological behavior. Jul 18, 2019 central giant cell granulomas are benign tumours of the mandible, presenting in children and young adults. Birgit kruselosler, raihanatou diallo, christoph jaffe2 in 1953. Central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a nonneoplastic proliferative lesion of unknown etiology. Dec 28, 2019 central giant cell granulomas of the condyle are rare. This article describes a case of central giant cell granuloma in the right posterior region of the mandible in a 10 yearold boy. Aggressive central giant cell granuloma mimicking peripheral. Pdf central giant cell granuloma cgcg is a benign intraosseous lesion of unknown etiology, and occurs in jaws.
257 888 1209 423 163 1358 359 813 724 434 572 1578 788 462 894 957 998 493 28 1179 207 1440 1470 683 631 340 117 1440 907 1325 434 391 1254 1184 1024